DDX5 (NM_004396) Human Recombinant Protein

• Background:

  This gene encodes a member of the DEAD box family of RNA helicases that are involved in a variety of cellular processes as a result of its role as an adaptor molecule, promoting interactions with a large number of other factors. This protein is involved in pathways that include the alteration of RNA structures, plays a role as a coregulator of transcription, a regulator of splicing, and in the processing of small noncoding RNAs. Members of this family contain nine conserved motifs, including the conserved Asp-Glu-Ala-Asp (DEAD) motif, important to ATP binding and hydrolysis as well as RNA binding and unwinding activities. Dysregulation of this gene may play a role in cancer development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2017]

• Synonyms:

  G17P1; HLR1; HUMP68; p68

• Gene ID:

  1655

• UniProt:

  P17844

• Accession Number mRNA:

  NM_004396

• Chromosomal Location:

  17q23.3

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Spliceosome

• Field of Research:

  Spliceosome

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Activity:

  2564974127148684

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  69 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  DDX5

• Species:

  Human

• Protein ID:

  NP_004387

• Overview:

  Recombinant protein of human DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 (DDX5)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/1655

• Uniprot URL:

  https://www.uniprot.org/uniprot/P17844

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_004396

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_004387