Torsin A (TOR1A) (NM_000113) Human Recombinant Protein

• Background:

  The protein encoded by this gene is a member of the AAA family of adenosine triphosphatases (ATPases), is related to the Clp protease/heat shock family and is expressed prominently in the substantia nigra pars compacta. Mutations in this gene result in the autosomal dominant disorder, torsion dystonia 1. [provided by RefSeq, Jul 2008]

• Synonyms:

  AMC5; DQ2; DYT1

• Gene ID:

  1861

• UniProt:

  O14656, B3KPA1

• Accession Number mRNA:

  NM_000113

• Chromosomal Location:

  9q34.11

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome, Protease

• Molecular Weight:

  37.6 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  TOR1A

• Species:

  Human

• Protein ID:

  NP_000104

• Overview:

  Recombinant protein of human torsin family 1, member A (torsin A) (TOR1A)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/1861

• Uniprot URL:

  https://www.uniprot.org/uniprot/O14656

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_000113

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_000104