RECQ1 (RECQL) (NM_032941) Human Recombinant Protein

• Background:

  The protein encoded by this gene is a member of the RecQ DNA helicase family. DNA helicases are enzymes involved in various types of DNA repair, including mismatch repair, nucleotide excision repair and direct repair. The encoded protein is involved in the processing of Holliday junctions, the suppression of sister chromatid exchanges, telomere maintenance, and is required for genotoxic stress resistance. Defects in this gene have been associated with several types of cancer. [provided by RefSeq, Jan 2017]

• Synonyms:

  RecQ1; RECQL1

• Gene ID:

  5965

• UniProt:

  P46063, A0A024RAV2

• Accession Number mRNA:

  NM_032941

• Chromosomal Location:

  12p12.1

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  73.3 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  RECQL

• Species:

  Human

• Protein ID:

  NP_116559

• Overview:

  Recombinant protein of human RecQ protein-like (DNA helicase Q1-like) (RECQL), transcript variant 2

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/5965

• Uniprot URL:

  https://www.uniprot.org/uniprot/P46063

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_032941

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_116559