LDOC1 (NM_012317) Human Recombinant Protein

• Background:

  The protein encoded by this gene contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB) . The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers. [provided by RefSeq, Jul 2008]

• Synonyms:

  BCUR1; Mar7; Mart7; RTL7; SIRH7

• Gene ID:

  23641

• UniProt:

  O95751

• Accession Number mRNA:

  NM_012317

• Chromosomal Location:

  Xq27.1

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  16.8 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  LDOC1

• Species:

  Human

• Protein ID:

  NP_036449

• Overview:

  Recombinant protein of human leucine zipper, down-regulated in cancer 1 (LDOC1)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/23641

• Uniprot URL:

  https://www.uniprot.org/uniprot/O95751

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_012317

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_036449