Emerin (EMD) (NM_000117) Human Recombinant Protein

• Background:

  Emerin is a serine-rich nuclear membrane protein and a member of the nuclear lamina-associated protein family. It mediates membrane anchorage to the cytoskeleton. Dreifuss-Emery muscular dystrophy is an X-linked inherited degenerative myopathy resulting from mutation in the emerin gene. [provided by RefSeq, Jul 2008]

• Synonyms:

  EDMD; LEMD5; STA

• Gene ID:

  2010

• UniProt:

  P50402

• Accession Number mRNA:

  NM_000117

• Chromosomal Location:

  Xq28

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM)

• Field of Research:

  Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM)

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome, Transmembrane

• Molecular Weight:

  28.8 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  EMD

• Species:

  Human

• Protein ID:

  NP_000108

• Overview:

  Recombinant protein of human emerin (EMD)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/2010

• Uniprot URL:

  https://www.uniprot.org/uniprot/P50402

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_000117

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_000108