FKBP1B (NM_054033) Human Recombinant Protein

• Background:

  The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is highly similar to the FK506-binding protein 1A. Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle. There are two alternatively spliced transcript variants of this gene encoding different isoforms. [provided by RefSeq, Jul 2008]

• Synonyms:

  FKBP1L; FKBP12.6; OTK4; PKBP1L; PPIase

• Gene ID:

  2281

• UniProt:

  P68106

• Accession Number mRNA:

  NM_054033

• Chromosomal Location:

  2p23.3

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome

• Molecular Weight:

  8.6 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  FKBP1B

• Species:

  Human

• Protein ID:

  NP_473374

• Overview:

  Recombinant protein of human FK506 binding protein 1B, 12.6 kDa (FKBP1B), transcript variant 2

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/2281

• Uniprot URL:

  https://www.uniprot.org/uniprot/P68106

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_054033

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_473374