TCP1 alpha (TCP1) (NM_030752) Human Recombinant Protein

• Background:

  The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC) . This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized. In addition, three pseudogenes that appear to be derived from this gene have been found. [provided by RefSeq, Jun 2010]

• Synonyms:

  CCT-alpha; CCT1; CCTa; D6S230E; TCP-1-alpha

• Gene ID:

  6950

• UniProt:

  P17987

• Accession Number mRNA:

  NM_030752

• Chromosomal Location:

  6q25.3

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  60.2 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  TCP1

• Species:

  Human

• Protein ID:

  NP_110379

• Overview:

  Recombinant protein of human t-complex 1 (TCP1), transcript variant 1

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/6950

• Uniprot URL:

  https://www.uniprot.org/uniprot/P17987

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_030752

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_110379