GTPBP3 (NM_032620) Human Recombinant Protein

• Background:

  This locus encodes a GTP-binding protein. The encoded protein is localized to the mitochondria and may play a role in mitochondrial tRNA modification. Polymorphisms at this locus may be associated with severity of aminoglycoside-induced deafness, a disease associated with a mutation in the 12S rRNA. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Sep 2010]

• Synonyms:

  COXPD23; GTPBG3; MSS1; MTGP1; THDF1

• Gene ID:

  84705

• UniProt:

  Q969Y2

• Accession Number mRNA:

  NM_032620

• Chromosomal Location:

  19p13.11

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  51.9 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  GTPBP3

• Species:

  Human

• Protein ID:

  NP_116009

• Overview:

  Recombinant protein of human GTP binding protein 3 (mitochondrial) (GTPBP3), nuclear gene encoding mitochondrial protein, transcript variant V

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/84705

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q969Y2

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_032620

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_116009