PUS1 (NM_025215) Human Recombinant Protein

• Background:

  This gene encodes a pseudouridine synthase that converts uridine to pseudouridine once it has been incorporated into an RNA molecule. The encoded enzyme may play an essential role in tRNA function and in stabilizing the secondary and tertiary structure of many RNAs. A mutation in this gene has been linked to mitochondrial myopathy and sideroblastic anemia. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Sep 2009]

• Synonyms:

  MLASA1

• Gene ID:

  80324

• UniProt:

  Q9Y606, E5KMT5

• Accession Number mRNA:

  NM_025215

• Chromosomal Location:

  12q24.33

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  47.3 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  PUS1

• Species:

  Human

• Protein ID:

  NP_079491

• Overview:

  Recombinant protein of human pseudouridylate synthase 1 (PUS1), transcript variant 1

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/80324

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9Y606

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_025215

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_079491