SSU72 (NM_014188) Human Recombinant Protein

• Background:

  Protein phosphatase that catalyzes the dephosphorylation of the C-terminal domain of RNA polymerase II. Plays a role in RNA processing and termination. Plays a role in pre-mRNA polyadenylation via its interaction with SYMPK.[UniProtKB/Swiss-Prot Function]

• Synonyms:

  HSPC182; PNAS-120

• Gene ID:

  29101

• UniProt:

  Q9NP77

• Accession Number mRNA:

  NM_014188

• Chromosomal Location:

  1p36.33

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome

• Molecular Weight:

  22.4 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  SSU72

• Species:

  Human

• Protein ID:

  NP_054907

• Overview:

  Recombinant protein of human SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae) (SSU72)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/29101

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9NP77

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_014188

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_054907