TIP49A (RUVBL1) (NM_003707) Human Recombinant Protein

• Background:

  This gene encodes a protein that has both DNA-dependent ATPase and DNA helicase activities and belongs to the ATPases associated with diverse cellular activities (AAA+) protein family. The encoded protein associates with several multisubunit transcriptional complexes and with protein complexes involved in both ATP-dependent remodeling and histone modification. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

• Synonyms:

  ECP-54; ECP54; INO80H; NMP 238; NMP238; PONTIN; Pontin52; RVB1; TIH1; TIP49; TIP49A

• Gene ID:

  8607

• UniProt:

  Q9Y265, A0A384MTR5

• Accession Number mRNA:

  NM_003707

• Chromosomal Location:

  3q21.3

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Wnt signaling pathway

• Field of Research:

  Wnt signaling pathway

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Stem cell - Pluripotency, Transcription Factors

• Molecular Weight:

  50 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  RUVBL1

• Species:

  Human

• Protein ID:

  NP_003698

• Overview:

  Recombinant protein of human RuvB-like 1 (E. coli) (RUVBL1)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/8607

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9Y265

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_003707

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_003698