ENT1 (SLC29A1) (NM_001078177) Human Recombinant Protein

• Background:

  This gene is a member of the equilibrative nucleoside transporter family. The gene encodes a transmembrane glycoprotein that localizes to the plasma and mitochondrial membranes and mediates the cellular uptake of nucleosides from the surrounding medium. The protein is categorized as an equilibrative (as opposed to concentrative) transporter that is sensitive to inhibition by nitrobenzylthioinosine (NBMPR) . Nucleoside transporters are required for nucleotide synthesis in cells that lack de novo nucleoside synthesis pathways, and are also necessary for the uptake of cytotoxic nucleosides used for cancer and viral chemotherapies. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008]

• Synonyms:

  ENT1

• Gene ID:

  2030

• UniProt:

  Q99808

• Accession Number mRNA:

  NM_001078177

• Chromosomal Location:

  6p21.1

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Transmembrane

• Molecular Weight:

  50 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  SLC29A1

• Species:

  Human

• Protein ID:

  NP_001071645

• Overview:

  Recombinant protein of human solute carrier family 29 (nucleoside transporters), member 1 (SLC29A1), nuclear gene encoding mitochondrial protein, transcript variant 1

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/2030

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q99808

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_001078177

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_001071645