Dehydrodolichyl Diphosphate Synthase (DHDDS) (NM_024887) Human Recombinant Protein

• Background:

  The protein encoded by this gene catalyzes cis-prenyl chain elongation to produce the polyprenyl backbone of dolichol, a glycosyl carrier lipid required for the biosynthesis of several classes of glycoproteins. Mutations in this gene are associated with retinitis pigmentosa type 59. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]

• Synonyms:

  CIT; CPT; DEDSM; DS; hCIT; HDS; RP59

• Gene ID:

  79947

• UniProt:

  Q86SQ9

• Accession Number mRNA:

  NM_024887

• Chromosomal Location:

  1p36.11

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Terpenoid backbone biosynthesis

• Field of Research:

  Terpenoid backbone biosynthesis

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  38.6 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  DHDDS

• Species:

  Human

• Protein ID:

  NP_079163

• Overview:

  Recombinant protein of human dehydrodolichyl diphosphate synthase (DHDDS), transcript variant 1

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/79947

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q86SQ9

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_024887

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_079163