NXT1 (NM_013248) Human Recombinant Protein

• Background:

  The protein encoded by this gene is located in the nuclear envelope. It has protein similarity to nuclear transport factor 2. This protein functions as a nuclear export factor in both RAN (Ras-related nuclear protein) - and CRM1 (required for chromosome region maintenance) -dependent pathways. It is found to stimulate the export of U1 snRNA in RAN- and CRM1-dependent pathways and the export of tRNA and mRNA in a CRM1-independent pathway. The encoded protein heterodimerizes with Tap protein and may regulate the ability of Tap protein to mediate nuclear mRNA export. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008]

• Synonyms:

  MTR2; P15

• Gene ID:

  29107

• UniProt:

  Q9UKK6

• Accession Number mRNA:

  NM_013248

• Chromosomal Location:

  20p11.21

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  15.7 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  NXT1

• Species:

  Human

• Protein ID:

  NP_037380

• Overview:

  Recombinant protein of human NTF2-like export factor 1 (NXT1)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/29107

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9UKK6

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_013248

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_037380