N myc interactor (NMI) (NM_004688) Human Recombinant Protein

• Background:

  NMYC interactor (NMI) encodes a protein that interacts with NMYC and CMYC (two members of the oncogene Myc family), and other transcription factors containing a Zip, HLH, or HLH-Zip motif. The NMI protein also interacts with all STATs except STAT2 and augments STAT-mediated transcription in response to cytokines IL2 and IFN-gamma. The NMI mRNA has low expression levels in all human fetal and adult tissues tested except brain and has high expression in cancer cell line-myeloid leukemias. [provided by RefSeq, Jul 2008]

• Synonyms:

  N-myc (and STAT) interactor; N-myc-interactor; N-myc and STAT interactor; N-myc interactor

• Gene ID:

  9111

• UniProt:

  Q13287

• Accession Number mRNA:

  NM_004688

• Chromosomal Location:

  2q23.3

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome, Transcription Factors

• Molecular Weight:

  34.9 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  NMI

• Species:

  Human

• Protein ID:

  NP_004679

• Overview:

  Recombinant protein of human N-myc (and STAT) interactor (NMI)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/9111

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q13287

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_004688

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_004679