FKBP2 (NM_057092) Human Recombinant Protein

• Background:

  The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is thought to function as an ER chaperone and may also act as a component of membrane cytoskeletal scaffolds. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2008]

• Synonyms:

  FKBP-13; FKBP13; PPIase

• Gene ID:

  2286

• UniProt:

  P26885, Q53XJ5

• Accession Number mRNA:

  NM_057092

• Chromosomal Location:

  11q13.1

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome

• Molecular Weight:

  13.3 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  FKBP2

• Species:

  Human

• Protein ID:

  NP_476433

• Overview:

  Recombinant protein of human FK506 binding protein 2, 13kDa (FKBP2), transcript variant 2

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/2286

• Uniprot URL:

  https://www.uniprot.org/uniprot/P26885

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_057092

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_476433