HDJ2 (DNAJA1) (NM_001539) Human Recombinant Protein

• Background:

  This gene encodes a member of the DnaJ family of proteins, which act as heat shock protein 70 cochaperones. Heat shock proteins facilitate protein folding, trafficking, prevention of aggregation, and proteolytic degradation. Members of this family are characterized by a highly conserved N-terminal J domain, a glycine/phenylalanine-rich region, four CxxCxGxG zinc finger repeats, and a C-terminal substrate-binding domain. The J domain mediates the interaction with heat shock protein 70 to recruit substrates and regulate ATP hydrolysis activity. In humans, this gene has been implicated in positive regulation of virus replication through co-option by the influenza A virus. Several pseudogenes of this gene are found on other chromosomes. [provided by RefSeq, Sep 2015]

• Synonyms:

  DJ-2; DjA1; hDJ-2; HDJ2; HSDJ; HSJ-2; HSJ2; HSPF4; NEDD7

• Gene ID:

  3301

• UniProt:

  P31689

• Accession Number mRNA:

  NM_001539

• Chromosomal Location:

  9p21.1

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome

• Molecular Weight:

  44.7 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  DNAJA1

• Species:

  Human

• Protein ID:

  NP_001530

• Overview:

  Recombinant protein of human DnaJ (Hsp40) homolog, subfamily A, member 1 (DNAJA1)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/3301

• Uniprot URL:

  https://www.uniprot.org/uniprot/P31689

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_001539

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_001530