CDT1 (NM_030928) Human Recombinant Protein

• Background:

  The protein encoded by this gene is involved in the formation of the pre-replication complex that is necessary for DNA replication. The encoded protein can bind geminin, which prevents replication and may function to prevent this protein from initiating replication at inappropriate origins. Phosphorylation of this protein by cyclin A-dependent kinases results in degradation of the protein. [provided by RefSeq, Mar 2011]

• Synonyms:

  DUP; RIS2

• Gene ID:

  81620

• UniProt:

  Q9H211

• Accession Number mRNA:

  NM_030928

• Chromosomal Location:

  16q24.3

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Stem cell - Pluripotency

• Molecular Weight:

  60.2 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  CDT1

• Species:

  Human

• Protein ID:

  NP_112190

• Overview:

  Recombinant protein of human chromatin licensing and DNA replication factor 1 (CDT1)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/81620

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9H211

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_030928

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_112190