AHA1 (AHSA1) (NM_012111) Human Recombinant Protein

• Background:

  Acts as a co-chaperone of HSP90AA1 (PubMed:29127155) . Activates the ATPase activity of HSP90AA1 leading to increase in its chaperone activity (PubMed:29127155) . Competes with the inhibitory co-chaperone FNIP1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins (PubMed:27353360) . Competes with the inhibitory co-chaperone TSC1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins (PubMed:29127155) .[UniProtKB/Swiss-Prot Function]

• Synonyms:

  AHA1; C14orf3; hAha1; p38

• Gene ID:

  10598

• UniProt:

  O95433

• Accession Number mRNA:

  NM_012111

• Chromosomal Location:

  14q24.3

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  38.1 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  AHSA1

• Species:

  Human

• Protein ID:

  NP_036243

• Overview:

  Recombinant protein of human AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) (AHSA1)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/10598

• Uniprot URL:

  https://www.uniprot.org/uniprot/O95433

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_012111

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_036243