HNRPH1 (HNRNPH1) (NM_005520) Human Recombinant Protein

• Background:

  This gene encodes a member of a subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs) . The hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA. These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some may shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNA and is very similar to the family member HNRPF. This gene may be associated with hereditary lymphedema type I. Alternatively spliced transcript variants have been described [provided by RefSeq, Mar 2012]

• Synonyms:

  HnRNPH; HNRPH; HNRPH1

• Gene ID:

  3187

• UniProt:

  P31943, A0A384MEJ3

• Accession Number mRNA:

  NM_005520

• Chromosomal Location:

  5q35.3

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  49 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  HNRNPH1

• Species:

  Human

• Protein ID:

  NP_005511

• Overview:

  Recombinant protein of human heterogeneous nuclear ribonucleoprotein H1 (H) (HNRNPH1)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/3187

• Uniprot URL:

  https://www.uniprot.org/uniprot/P31943

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_005520

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_005511