RSK3 (RPS6KA2) (NM_021135) Human Recombinant Protein

• Background:

  This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains two non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternative splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jan 2016]

• Synonyms:

  HU-2; MAPKAPK1C; p90-RSK3; p90RSK2; pp90RSK3; RSK; RSK3; S6K-alpha; S6K-alpha2

• Gene ID:

  6196

• UniProt:

  Q15349

• Accession Number mRNA:

  NM_021135

• Chromosomal Location:

  6q27

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Long-term potentiation, MAPK signaling pathway, mTOR signaling pathway, Neurotrophin signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation

• Field of Research:

  Long-term potentiation, MAPK signaling pathway, mTOR signaling pathway, Neurotrophin signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome, Protein Kinase

• Molecular Weight:

  83.1 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  RPS6KA2

• Species:

  Human

• Protein ID:

  NP_066958

• Overview:

  Recombinant protein of human ribosomal protein S6 kinase, 90kDa, polypeptide 2 (RPS6KA2), transcript variant 1

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/6196

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q15349

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_021135

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_066958