14 3 3 gamma (YWHAG) (NM_012479) Human Recombinant Protein

• Background:

  This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the rat ortholog. It is induced by growth factors in human vascular smooth muscle cells, and is also highly expressed in skeletal and heart muscles, suggesting an important role for this protein in muscle tissue. It has been shown to interact with RAF1 and protein kinase C, proteins involved in various signal transduction pathways. [provided by RefSeq, Jul 2008]

• Synonyms:

  14-3-3GAMMA; DEE56; EIEE56; PPP1R170

• Gene ID:

  7532

• UniProt:

  P61981

• Accession Number mRNA:

  NM_012479

• Chromosomal Location:

  7q11.23

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Cell cycle, Neurotrophin signaling pathway, Oocyte meiosis

• Field of Research:

  Cell cycle, Neurotrophin signaling pathway, Oocyte meiosis

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome

• Molecular Weight:

  28.1 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  YWHAG

• Species:

  Human

• Protein ID:

  NP_036611

• Overview:

  Recombinant protein of human tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide (YWHAG)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/7532

• Uniprot URL:

  https://www.uniprot.org/uniprot/P61981

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_012479

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_036611