ODF2 (NM_002540) Human Recombinant Protein

• Background:

  The outer dense fibers are cytoskeletal structures that surround the axoneme in the middle piece and principal piece of the sperm tail. The fibers function in maintaining the elastic structure and recoil of the sperm tail as well as in protecting the tail from shear forces during epididymal transport and ejaculation. Defects in the outer dense fibers lead to abnormal sperm morphology and infertility. This gene encodes one of the major outer dense fiber proteins. Alternative splicing results in multiple transcript variants. The longer transcripts, also known as 'Cenexins', encode proteins with a C-terminal extension that are differentially targeted to somatic centrioles and thought to be crucial for the formation of microtubule organizing centers. [provided by RefSeq, Oct 2010]

• Synonyms:

  CT134; ODF2/1; ODF2/2; ODF84

• Gene ID:

  4957

• UniProt:

  Q5BJF6, A0A024R8A5

• Accession Number mRNA:

  NM_002540

• Chromosomal Location:

  9q34.11

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  93.1 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  ODF2

• Species:

  Human

• Protein ID:

  NP_002531

• Overview:

  Recombinant protein of human outer dense fiber of sperm tails 2 (ODF2), transcript variant 1

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/4957

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q5BJF6

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_002540

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_002531