NEUROD1 (NM_002500) Human Recombinant Protein

• Background:

  This gene encodes a member of the NeuroD family of basic helix-loop-helix (bHLH) transcription factors. The protein forms heterodimers with other bHLH proteins and activates transcription of genes that contain a specific DNA sequence known as the E-box. It regulates expression of the insulin gene, and mutations in this gene result in type II diabetes mellitus. [provided by RefSeq, Jul 2008]

• Synonyms:

  BETA2; BHF-1; bHLHa3; MODY6; NEUROD; T2D

• Gene ID:

  4760

• UniProt:

  Q13562

• Accession Number mRNA:

  NM_002500

• Chromosomal Location:

  2q31.3

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Maturity onset diabetes of the young

• Field of Research:

  Maturity onset diabetes of the young

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Adult stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Transcription Factors

• Molecular Weight:

  39.7 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  NEUROD1

• Species:

  Human

• Protein ID:

  NP_002491

• Overview:

  Recombinant protein of human neurogenic differentiation 1 (NEUROD1)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/4760

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q13562

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_002500

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_002491