Frequenin (NCS1) (NM_014286) Human Recombinant Protein

• Background:

  This gene is a member of the neuronal calcium sensor gene family, which encode calcium-binding proteins expressed predominantly in neurons. The protein encoded by this gene regulates G protein-coupled receptor phosphorylation in a calcium-dependent manner and can substitute for calmodulin. The protein is associated with secretory granules and modulates synaptic transmission and synaptic plasticity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

• Synonyms:

  FLUP; FREQ

• Gene ID:

  23413

• UniProt:

  P62166, A0A024R8B2

• Accession Number mRNA:

  NM_014286

• Chromosomal Location:

  9q34.11

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome

• Molecular Weight:

  21.7 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  NCS1

• Species:

  Human

• Protein ID:

  NP_055101

• Overview:

  Recombinant protein of human frequenin homolog (Drosophila) (FREQ), transcript variant 1

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/23413

• Uniprot URL:

  https://www.uniprot.org/uniprot/P62166

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_014286

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_055101