VEGFB (NM_003377) Human Recombinant Protein

• Background:

  This gene encodes a member of the PDGF (platelet-derived growth factor) /VEGF (vascular endothelial growth factor) family. The VEGF family members regulate the formation of blood vessels and are involved in endothelial cell physiology. This member is a ligand for VEGFR-1 (vascular endothelial growth factor receptor 1) and NRP-1 (neuropilin-1) . Studies in mice showed that this gene was co-expressed with nuclear-encoded mitochondrial genes and the encoded protein specifically controlled endothelial uptake of fatty acids. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Sep 2011]

• Synonyms:

  VEGFL; VRF

• Gene ID:

  7423

• UniProt:

  P49765, Q7LAP4

• Accession Number mRNA:

  NM_003377

• Chromosomal Location:

  11q13.1

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Bladder cancer, Cytokine-cytokine receptor interaction, Focal adhesion, mTOR signaling pathway, Pancreatic cancer, Pathways in cancer, Renal cell carcinoma

• Field of Research:

  Bladder cancer, Cytokine-cytokine receptor interaction, Focal adhesion, mTOR signaling pathway, Pancreatic cancer, Pathways in cancer, Renal cell carcinoma

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome, Secreted Protein

• Molecular Weight:

  21.4 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  VEGFB

• Species:

  Human

• Protein ID:

  NP_003368

• Overview:

  Recombinant protein of human vascular endothelial growth factor B (VEGFB)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/7423

• Uniprot URL:

  https://www.uniprot.org/uniprot/P49765

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_003377

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_003368