CTP synthase (CTPS1) (NM_001905) Human Recombinant Protein

• Background:

  This gene encodes an enzyme responsible for the catalytic conversion of UTP (uridine triphosphate) to CTP (cytidine triphospate) . This reaction is an important step in the biosynthesis of phospholipids and nucleic acids. Activity of this proten is important in the immune system, and loss of function of this gene has been associated with immunodeficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

• Synonyms:

  CTPS; GATD5; GATD5A; IMD24

• Gene ID:

  1503

• UniProt:

  P17812

• Accession Number mRNA:

  NM_001905

• Chromosomal Location:

  1p34.2

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Metabolic pathways, Pyrimidine metabolism

• Field of Research:

  Metabolic pathways, Pyrimidine metabolism

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  66.5 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  CTPS1

• Species:

  Human

• Protein ID:

  NP_001896

• Overview:

  Recombinant protein of human CTP synthase (CTPS)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/1503

• Uniprot URL:

  https://www.uniprot.org/uniprot/P17812

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_001905

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_001896