CSNK2A2 (NM_001896) Human Recombinant Protein

• Background:

  This gene encodes the alpha', or alpha 2, catalytic subunit of the protein kinase enzyme, casein kinase 2 (CK2) . Casein kinase 2 is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. It is involved in various cellular processes, including cell cycle control, apoptosis, and circadian rhythms. This heterotetrameric kinase includes two catalytic subunits, either alpha or alpha', and two regulatory beta subunits. The closely related gene paralog encoding the alpha, or alpha 1 subunit (CSNK2A1, Gene ID: 1457) is found on chromosome 20. An intronic variant in this gene (alpha 2) may be associated with leukocyte telomere length in a South Asian population. A related transcribed pseudogene is found on chromosome 11. [provided by RefSeq, Aug 2017]

• Synonyms:

  CK2A2; CK2alpha'; CSNK2A1

• Gene ID:

  1459

• UniProt:

  P19784

• Accession Number mRNA:

  NM_001896

• Chromosomal Location:

  16q21

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Adherens junction, Tight junction, Wnt signaling pathway

• Field of Research:

  Adherens junction, Tight junction, Wnt signaling pathway

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome, Protein Kinase

• Molecular Weight:

  41 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  CSNK2A2

• Species:

  Human

• Protein ID:

  NP_001887

• Overview:

  Recombinant protein of human casein kinase 2, alpha prime polypeptide (CSNK2A2)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/1459

• Uniprot URL:

  https://www.uniprot.org/uniprot/P19784

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_001896

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_001887