RIP2 (RIPK2) (NM_003821) Human Recombinant Protein

• Background:

  This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein contains a C-terminal caspase activation and recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-kappaB and inducer of apoptosis in response to various stimuli. [provided by RefSeq, Jul 2008]

• Synonyms:

  CARD3; CARDIAK; CCK; GIG30; RICK; RIP2

• Gene ID:

  8767

• UniProt:

  O43353, A0A0S2Z4Z8

• Accession Number mRNA:

  NM_003821

• Chromosomal Location:

  8q21.3

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Neurotrophin signaling pathway, NOD-like receptor signaling pathway

• Field of Research:

  Neurotrophin signaling pathway, NOD-like receptor signaling pathway

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome, Protein Kinase

• Molecular Weight:

  61 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  RIPK2

• Species:

  Human

• Protein ID:

  NP_003812

• Overview:

  Recombinant protein of human receptor-interacting serine-threonine kinase 2 (RIPK2)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/8767

• Uniprot URL:

  https://www.uniprot.org/uniprot/O43353

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_003821

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_003812