RPRM (NM_019845) Human Recombinant Protein

• Background:

  May be involved in the regulation of p53-dependent G2 arrest of the cell cycle. Seems to induce cell cycle arrest by inhibiting CDK1 activity and nuclear translocation of the CDC2 cyclin B1 complex (By similarity) .[UniProtKB/Swiss-Prot Function]

• Synonyms:

  REPRIMO

• Gene ID:

  56475

• UniProt:

  Q9NS64

• Accession Number mRNA:

  NM_019845

• Chromosomal Location:

  2q23.3

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  P53 signaling pathway

• Field of Research:

  P53 signaling pathway

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Transmembrane

• Molecular Weight:

  11.6 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  RPRM

• Species:

  Human

• Protein ID:

  NP_062819

• Overview:

  Recombinant protein of human reprimo, TP53 dependent G2 arrest mediator candidate (RPRM)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/56475

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9NS64

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_019845

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_062819