MAD2L1 binding protein (MAD2L1BP) (NM_014628) Human Recombinant Protein

• Background:

  The protein encoded by this gene was identified as a binding protein of the MAD2 mitotic arrest deficient-like 1 (MAD2/MAD2L1) . MAD2 is a key component of the spindle checkpoint that delays the onset of anaphase until all the kinetochores are attached to the spindle. This protein may interact with the spindle checkpoint and coordinate cell cycle events in late mitosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]

• Synonyms:

  CMT2

• Gene ID:

  9587

• UniProt:

  Q15013

• Accession Number mRNA:

  NM_014628

• Chromosomal Location:

  6p21.1

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome

• Molecular Weight:

  30.9 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  MAD2L1BP

• Species:

  Human

• Protein ID:

  NP_055443

• Overview:

  Recombinant protein of human MAD2L1 binding protein (MAD2L1BP), transcript variant 2

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/9587

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q15013

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_014628

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_055443