Carboxypeptidase A (CPA1) (NM_001868) Human Recombinant Protein

• Background:

  This gene encodes a member of the carboxypeptidase A family of zinc metalloproteases. This enzyme is produced in the pancreas and preferentially cleaves C-terminal branched-chain and aromatic amino acids from dietary proteins. This gene and several family members are present in a gene cluster on chromosome 7. Mutations in this gene may be linked to chronic pancreatitis, while elevated protein levels may be associated with pancreatic cancer. [provided by RefSeq, Jan 2015]

• Synonyms:

  CPA

• Gene ID:

  1357

• UniProt:

  P15085

• Accession Number mRNA:

  NM_001868

• Chromosomal Location:

  7q32.2

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome, ES Cell Differentiation/IPS, Protease, Secreted Protein

• Molecular Weight:

  45.5 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  CPA1

• Species:

  Human

• Protein ID:

  NP_001859

• Overview:

  Recombinant protein of human carboxypeptidase A1 (pancreatic) (CPA1)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/1357

• Uniprot URL:

  https://www.uniprot.org/uniprot/P15085

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_001868

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_001859