TXNL2 (GLRX3) (NM_006541) Human Recombinant Protein

• Background:

  This gene encodes a member of the glutaredoxin family. Glutaredoxins are oxidoreductase enzymes that reduce a variety of substrates using glutathione as a cofactor. The encoded protein binds to and modulates the function of protein kinase C theta. The encoded protein may also inhibit apoptosis and play a role in cellular growth, and the expression of this gene may be a marker for cancer. Pseudogenes of this gene are located on the short arm of chromosomes 6 and 9. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2010]

• Synonyms:

  GLRX4; GRX3; GRX4; PICOT; TXNL2; TXNL3

• Gene ID:

  10539

• UniProt:

  O76003, A0A140VJK1

• Accession Number mRNA:

  NM_006541

• Chromosomal Location:

  10q26.3

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome

• Molecular Weight:

  37.3 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  GLRX3

• Species:

  Human

• Protein ID:

  NP_006532

• Overview:

  Recombinant protein of human glutaredoxin 3 (GLRX3)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/10539

• Uniprot URL:

  https://www.uniprot.org/uniprot/O76003

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_006541

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_006532