CDK7 (NM_001799) Human Recombinant Protein

• Background:

  The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK) . It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle. [provided by RefSeq, Jul 2008]

• Synonyms:

  CAK; CAK1; CDKN7; HCAK; MO15; p39MO15; STK1

• Gene ID:

  1022

• UniProt:

  P50613, A0A0S2Z3F9

• Accession Number mRNA:

  NM_001799

• Chromosomal Location:

  5q13.2

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Cell cycle, Nucleotide excision repair

• Field of Research:

  Cell cycle, Nucleotide excision repair

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome, Protein Kinase, Stem cell - Pluripotency, Transcription Factors

• Molecular Weight:

  38.9 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  CDK7

• Species:

  Human

• Protein ID:

  NP_001790

• Overview:

  Recombinant protein of human cyclin-dependent kinase 7 (CDK7)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/1022

• Uniprot URL:

  https://www.uniprot.org/uniprot/P50613

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_001799

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_001790