Serum Amyloid P (APCS) (NM_001639) Human Recombinant Protein

• Background:

  The protein encoded by this gene is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo. [provided by RefSeq, Sep 2008]

• Synonyms:

  HEL-S-92n; PTX2; SAP

• Gene ID:

  325

• UniProt:

  P02743, V9HWP0

• Accession Number mRNA:

  NM_001639

• Chromosomal Location:

  1q23.2

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome, Secreted Protein

• Molecular Weight:

  23.2 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  APCS

• Species:

  Human

• Protein ID:

  NP_001630

• Overview:

  Recombinant protein of human amyloid P component, serum (APCS)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/325

• Uniprot URL:

  https://www.uniprot.org/uniprot/P02743

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_001639

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_001630