AP2S1 (NM_004069) Human Recombinant Protein

• Background:

  One of two major clathrin-associated adaptor complexes, AP-2, is a heterotetramer which is associated with the plasma membrane. This complex is composed of two large chains, a medium chain, and a small chain. This gene encodes the small chain of this complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

• Synonyms:

  AP17; CLAPS2; FBH3; FBHOk; HHC3

• Gene ID:

  1175

• UniProt:

  P53680

• Accession Number mRNA:

  NM_004069

• Chromosomal Location:

  19q13.32

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Endocytosis, Huntington's disease

• Field of Research:

  Endocytosis, Huntington's disease

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  16.8 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  AP2S1

• Species:

  Human

• Protein ID:

  NP_004060

• Overview:

  Recombinant protein of human adaptor-related protein complex 2, sigma 1 subunit (AP2S1), transcript variant AP17

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/1175

• Uniprot URL:

  https://www.uniprot.org/uniprot/P53680

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_004069

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_004060