TRNT1 (NM_016000) Human Recombinant Protein

• Background:

  The protein encoded by this gene is a CCA-adding enzyme which belongs to the tRNA nucleotidyltransferase/poly (A) polymerase family. This essential enzyme functions by catalyzing the addition of the conserved nucleotide triplet CCA to the 3' terminus of tRNA molecules. Mutations in this gene result in sideroblastic anemia with B-cell immunodeficiency, periodic fevers, and developmental delay. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]

• Synonyms:

  CCA1; CCA1, MtCCA, CGI-47; CGI-47; mitochondrial CCA-adding tRNA-nucleotidyltransferase; MtCCA; tRNA nucleotidyl transferase, CCA-adding, 1

• Gene ID:

  51095

• UniProt:

  Q96Q11

• Accession Number mRNA:

  NM_016000

• Chromosomal Location:

  3p26.2

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  46.8

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  TRNT1

• Species:

  Human

• Protein ID:

  NP_057084

• Overview:

  Recombinant protein of human tRNA nucleotidyl transferase, CCA-adding, 1 (TRNT1), transcript variant 1

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/51095

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q96Q11

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_016000

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_057084