GST3 (GSTP1) (NM_000852) Human Recombinant Protein

• Background:

  Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. This GST family member is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases. [provided by RefSeq, Jul 2008]

• Synonyms:

  DFN7; FAEES3; GST3; GSTP; HEL-S-22; PI

• Gene ID:

  2950

• UniProt:

  P09211, V9HWE9

• Accession Number mRNA:

  NM_000852

• Chromosomal Location:

  11q13.2

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Drug metabolism - cytochrome P450, Glutathione metabolism, Metabolism of xenobiotics by cytochrome P450, Pathways in cancer, Prostate cancer

• Field of Research:

  Drug metabolism - cytochrome P450, Glutathione metabolism, Metabolism of xenobiotics by cytochrome P450, Pathways in cancer, Prostate cancer

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome

• Molecular Weight:

  23.2 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  GSTP1

• Species:

  Human

• Protein ID:

  NP_000843

• Overview:

  Recombinant protein of human glutathione S-transferase pi 1 (GSTP1)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/2950

• Uniprot URL:

  https://www.uniprot.org/uniprot/P09211

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_000852

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_000843