Cystatin A (CSTA) (NM_005213) Human Recombinant Protein

• Background:

  The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins, and kininogens. This gene encodes a stefin that functions as a cysteine protease inhibitor, forming tight complexes with papain and the cathepsins B, H, and L. The protein is one of the precursor proteins of cornified cell envelope in keratinocytes and plays a role in epidermal development and maintenance. Stefins have been proposed as prognostic and diagnostic tools for cancer. [provided by RefSeq, Jul 2008]

• Synonyms:

  AREI; PSS4; STF1; STFA

• Gene ID:

  1475

• UniProt:

  P01040

• Accession Number mRNA:

  NM_005213

• Chromosomal Location:

  3q21.1

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  10.8 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  CSTA

• Species:

  Human

• Protein ID:

  NP_005204

• Overview:

  Recombinant protein of human cystatin A (stefin A) (CSTA)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/1475

• Uniprot URL:

  https://www.uniprot.org/uniprot/P01040

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_005213

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_005204