Trfp (MED20) (NM_004275) Human Recombinant Protein

• Background:

  This gene encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, by interacting with RNA polymerase II and promoting the formation of a transcriptional pre-initiation complex. A mutation in this gene has been associated with a novel infantile-onset neurodegenerative movement disorder. Alternatively spliced transcript variants have been identified. [provided by RefSeq, Mar 2015]

• Synonyms:

  PRO0213; SRB2; TRFP

• Gene ID:

  9477

• UniProt:

  Q9H944

• Accession Number mRNA:

  NM_004275

• Chromosomal Location:

  6p21.1

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  23 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  MED20

• Species:

  Human

• Protein ID:

  NP_004266

• Overview:

  Recombinant protein of human mediator complex subunit 20 (MED20)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/9477

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9H944

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_004275

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_004266