STK25 (NM_006374) Human Recombinant Protein

• Background:

  This gene encodes a member of the germinal centre kinase III (GCK III) subfamily of the sterile 20 superfamily of kinases. The encoded enzyme plays a role in serine-threonine liver kinase B1 (LKB1) signaling pathway to regulate neuronal polarization and morphology of the Golgi apparatus. The protein is translocated from the Golgi apparatus to the nucleus in response to chemical anoxia and plays a role in regulation of cell death. A pseudogene associated with this gene is located on chromosome 18. Multiple alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2012]

• Synonyms:

  SOK1; YSK1

• Gene ID:

  10494

• UniProt:

  O00506, A0A024R4B2

• Accession Number mRNA:

  NM_006374

• Chromosomal Location:

  2q37.3

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome, Protein Kinase

• Molecular Weight:

  47.9 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  STK25

• Species:

  Human

• Protein ID:

  NP_006365

• Overview:

  Purified recombinant protein of Homo sapiens serine/threonine kinase 25 (STE20 homolog, yeast) (STK25)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/10494

• Uniprot URL:

  https://www.uniprot.org/uniprot/O00506

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_006374

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_006365