BRMS1 (NM_015399) Human Recombinant Protein

• Background:

  This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC) . The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

• Synonyms:

  DKFZp564A063

• Gene ID:

  25855

• UniProt:

  Q9HCU9

• Accession Number mRNA:

  NM_015399

• Chromosomal Location:

  11q13.2

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome

• Molecular Weight:

  28.3 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  BRMS1

• Species:

  Human

• Protein ID:

  NP_056214

• Overview:

  Recombinant protein of human breast cancer metastasis suppressor 1 (BRMS1), transcript variant 1

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/25855

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9HCU9

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_015399

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_056214