CUL4A (NM_003589) Human Recombinant Protein

• Background:

  CUL4A is the ubiquitin ligase component of a multimeric complex involved in the degradation of DNA damage-response proteins (Liu et al., 2009 [PubMed 19481525]) .[supplied by OMIM, Oct 2009]

• Synonyms:

  Cullin 4A; OTTHUMP00000018753; OTTHUMP00000018754

• Gene ID:

  8451

• UniProt:

  Q13619

• Accession Number mRNA:

  NM_003589

• Chromosomal Location:

  13q34

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Nucleotide excision repair, Ubiquitin mediated proteolysis

• Field of Research:

  Nucleotide excision repair, Ubiquitin mediated proteolysis

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  76.6 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  CUL4A

• Species:

  Human

• Protein ID:

  NP_003580

• Overview:

  Purified recombinant protein of Homo sapiens cullin 4A (CUL4A), transcript variant 2

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/8451

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q13619

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_003589

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_003580