COUP TF1 (NR2F1) (NM_005654) Human Recombinant Protein

• Background:

  The protein encoded by this gene is a nuclear hormone receptor and transcriptional regulator. The encoded protein acts as a homodimer and binds to 5'-AGGTCA-3' repeats. Defects in this gene are a cause of Bosch-Boonstra optic atrophy syndrome (BBOAS) . [provided by RefSeq, Apr 2014]

• Synonyms:

  BBOAS; BBSOAS; COUP-TFI; EAR-3; EAR3; ERBAL3; NR2F2; SVP44; TCFCOUP1; TFCOUP1

• Gene ID:

  7025

• UniProt:

  P10589

• Accession Number mRNA:

  NM_005654

• Chromosomal Location:

  5q15

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome, Nuclear Hormone Receptor, Transcription Factors

• Molecular Weight:

  46 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  NR2F1

• Species:

  Human

• Protein ID:

  NP_005645

• Overview:

  Recombinant protein of human nuclear receptor subfamily 2, group F, member 1 (NR2F1)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/7025

• Uniprot URL:

  https://www.uniprot.org/uniprot/P10589

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_005654

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_005645