NIP30 (FAM192A) (NM_024946) Human Recombinant Protein

• Background:

  Promotes the association of the proteasome activator complex subunit PSME3 with the 20S proteasome and regulates its activity. Inhibits PSME3-mediated degradation of some proteasome substrates, probably by affecting their diffusion rate into the catalytic chamber of the proteasome. Also inhibits the interaction of PSME3 with COIL, inhibits accumulation of PSME3 in Cajal bodies and positively regulates the number of Cajal bodies in the nucleus.[UniProtKB/Swiss-Prot Function]

• Synonyms:

  C16orf94; CDA018; CDA10; FAM192A; NIP30; PIP30

• Gene ID:

  80011

• UniProt:

  Q9GZU8, A0A024R6T8

• Accession Number mRNA:

  NM_024946

• Chromosomal Location:

  16q13

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Activity:

  29804834

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  28.7 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  FAM192A

• Species:

  Human

• Protein ID:

  NP_079222

• Overview:

  Recombinant protein of human NEFA-interacting nuclear protein NIP30 (NIP30)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/80011

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9GZU8

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_024946

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_079222