TFIIB (GTF2B) (NM_001514) Human Recombinant Protein

• Background:

  This gene encodes the general transcription factor IIB, one of the ubiquitous factors required for transcription initiation by RNA polymerase II. The protein localizes to the nucleus where it forms a complex (the DAB complex) with transcription factors IID and IIA. Transcription factor IIB serves as a bridge between IID, the factor which initially recognizes the promoter sequence, and RNA polymerase II. [provided by RefSeq, Jul 2008]

• Synonyms:

  TF2B; TFIIB

• Gene ID:

  2959

• UniProt:

  Q00403

• Accession Number mRNA:

  NM_001514

• Chromosomal Location:

  1p22.2

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Basal transcription factors

• Field of Research:

  Basal transcription factors

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome, Transcription Factors

• Molecular Weight:

  34.7 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  GTF2B

• Species:

  Human

• Protein ID:

  NP_001505

• Overview:

  Recombinant protein of human general transcription factor IIB (GTF2B)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/2959

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q00403

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_001514

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_001505