VPREB3 (NM_013378) Human Recombinant Protein

• Background:

  The protein encoded by this gene is the human ortholog of the mouse VpreB3 (8HS20) protein, is thought to be involved in B-cell maturation, and may play a role in assembly of the pre-B cell receptor (pre-BCR) . While the role of this protein in B-cell development has not yet been elucidated, studies with the chicken ortholog of this protein have found that when overexpressed, this protein localizes to the endoplasmic reticulum. The mouse ortholog of this protein has been shown to associate with membrane mu heavy chains early in the course of pre-B cell receptor biosynthesis. Expression of this gene has been observed in some lymphomas. [provided by RefSeq, Apr 2015]

• Synonyms:

  8HS20; N27C7-2

• Gene ID:

  29802

• UniProt:

  Q9UKI3

• Accession Number mRNA:

  NM_013378

• Chromosomal Location:

  22q11

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome

• Molecular Weight:

  13.5 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  VPREB3

• Species:

  Human

• Protein ID:

  NP_037510

• Overview:

  Recombinant protein of human pre-B lymphocyte 3 (VPREB3)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/29802

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9UKI3

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_013378

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_037510