MD2 (LY96) (NM_015364) Human Recombinant Protein

• Background:

  This gene encodes a protein which associates with toll-like receptor 4 on the cell surface and confers responsiveness to lipopolysaccyaride (LPS), thus providing a link between the receptor and LPS signaling. Studies of the mouse ortholog suggest that this gene may be involved in endotoxin neutralization. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2010]

• Synonyms:

  ESOP-1; ly-96; MD-2; MD2

• Gene ID:

  23643

• UniProt:

  Q9Y6Y9

• Accession Number mRNA:

  NM_015364

• Chromosomal Location:

  8q21.11

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Pathogenic Escherichia coli infection, Toll-like receptor signaling pathway

• Field of Research:

  Pathogenic Escherichia coli infection, Toll-like receptor signaling pathway

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Activity:

  25605324

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Secreted Protein

• Molecular Weight:

  18.4 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  LY96

• Species:

  Human

• Protein ID:

  NP_056179

• Overview:

  Recombinant protein of human lymphocyte antigen 96 (LY96)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/23643

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9Y6Y9

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_015364

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_056179