C3AR1 (NM_004054) Human Recombinant Protein

• Background:

  C3a is an anaphylatoxin released during activation of the complement system. The protein encoded by this gene is an orphan G protein-coupled receptor for C3a. Binding of C3a by the encoded receptor activates chemotaxis, granule enzyme release, superoxide anion production, and bacterial opsonization. [provided by RefSeq, May 2016]

• Synonyms:

  AZ3B; C3AR; HNFAG09

• Gene ID:

  719

• UniProt:

  Q16581, A8K2H7

• Accession Number mRNA:

  NM_004054

• Chromosomal Location:

  12p13.31

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Complement and coagulation cascades, Neuroactive ligand-receptor interaction

• Field of Research:

  Complement and coagulation cascades, Neuroactive ligand-receptor interaction

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome, GPCR, Transmembrane

• Molecular Weight:

  53.7 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  C3AR1

• Species:

  Human

• Protein ID:

  NP_004045

• Overview:

  Recombinant protein of human complement component 3a receptor 1 (C3AR1)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/719

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q16581

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_004054

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_004045