C4BPA (NM_000715) Human Recombinant Protein

• Background:

  This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. Along with a single, unique beta-chain, seven identical alpha-chains encoded by this gene assemble into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Two pseudogenes of this gene are also found in the cluster. [provided by RefSeq, Jul 2008]

• Synonyms:

  C4BP; PRP

• Gene ID:

  722

• UniProt:

  P04003

• Accession Number mRNA:

  NM_000715

• Chromosomal Location:

  1q32.2

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Complement and coagulation cascades

• Field of Research:

  Complement and coagulation cascades

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  61.6 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  C4BPA

• Species:

  Human

• Protein ID:

  NP_000706

• Overview:

  Recombinant protein of human complement component 4 binding protein, alpha (C4BPA)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/722

• Uniprot URL:

  https://www.uniprot.org/uniprot/P04003

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_000715

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_000706